Where do we start? Public water fluoridation is implicated in almost every degenerative disease known. Some aspects of this research, such as what we are finding about damage to the pineal gland, have only been conducted since the early 1990’s. Surely, every family has been touched by one of the following afflictions. We need to start asking ourselves why and doing something about it.

It’s imperative to assess these very real risks. Nonetheless, policy makers attempt to invert logic into the conversation, saying it’s not obvious that fluoridation is creating or exacerbating these issues, thus it’s OK because of “no adverse health effects” (read, no immediate negative health effects). This astounding reversal of common sense and medical practice is masterful propaganda, but is standard in public health policy agencies. We know better.


It is generally accepted that if a substance can induce genetic damage there is a heightened risk that it could cause cancer as well. According to the National Toxicology Program, "the preponderance of evidence" from laboratory 'in vitro' studies indicates that fluoride is a mutagen (a compound that can cause genetic damage). Of additional concern are recent studies indicating that:

  • Primates (humans and great apes) are more susceptible to the mutagenic effects of fluoride than rodents (rats).
  • An increased rate of mutagenic damage was detectable in humans exposed to only modestly elevated levels of fluoride.
  • Workers exposed to fluoride in industry - in the absence of other known carcinogens such as PAH - suffered an increased occurrence of bladder cancer.


Is fluoride in part the reason for near epidemic levels of hypothyroidism in the United States? Wilmington, NC has one of the highest incidences of thyroid disease in the country.

The thyroid needs iodine (I) to function properly and most people are iodine (I) deficient. Fluoride and iodine, both being members of the halogens group of atoms, have an antagonistic relationship. When there is excess of fluoride in the body it can interfere with the function of the thyroid gland, especially in the case of iodine deficiency. It is possible that iodine deficiency, which is the most common cause of brain damage and mental disability in the world, could be lessened by simply cutting back on the use of fluoride.


Up until the 1990s, no research had ever been conducted to determine the impact of fluoride on the pineal gland - a small gland located between the two hemispheres of the brain that regulates the production of the hormone melatonin. Melatonin is a hormone that helps regulate the onset of puberty and helps protect the body from cell damage caused by free radicals. The pineal gland is also thought to perform functions beyond the grasp of modern science, including the regulation of consciousness.

It is now known - thanks to the meticulous research of Dr. Jennifer Luke from the University of Surrey in England - that the pineal gland is the primary target of fluoride accumulation within the body. This research was finished in 1998, it is very telling that it has not been reproduced in the United States, or elsewhere for that matter. Why would we not want to further research on an issue that potentially undermines the human experience?

Quoting Dr. Luke :“The single animal study of pineal function indicates that fluoride exposure results in altered melatonin production and altered timing of sexual maturity. Whether fluoride affects pineal function in humans remains to be demonstrated. The two studies of menarcheal age in humans show the possibility of earlier menarche in some individuals exposed to fluoride, but no definitive statement can be made. Recent information on the role of the pineal organ in humans suggests that any agent that affects pineal function could affect human health in a variety of ways, including effects on sexual maturation, calcium metabolism, parathyroid function, postmenopausal osteoporosis, cancer, and psychiatric disease.” (SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p221-22.)


  1. Fluoride's ability to damage the brain represents one of the most active areas of research on fluoride toxicity today.
  2. The research on fluoride and the brain has been fueled by 18 human studies from China, India, Iran, and Mexico finding elevated levels of fluoride exposure to be associated with IQ deficits in children. Fluoride's impact on IQ is exacerbated among children with low-iodine exposure.
  3. The impact of fluoride on children's IQ has been documented even after controlling for children's lead exposure, iodine exposure, parental education and income status, and other known factors that might impact the results (Rocha-Amador 2007; Xiang 2003 a,b).
  4. In addition to IQ studies, 3 studies (Yu 1996; Du 1992; Han 1989) have found that fluoride accumulates in the brain of the fetus, causing damage to cells and neurotransmitters and 1 study (Li 2004) has found a correlation between exposure to fluoride during fetal development and behavioral deficits among neonates.
  5. Several recent studies have found that even adult exposures to fluoride may result in central nervous system disturbances, particularly among industrial workers.
  6. The findings of neurological effects in fluoride-exposed humans is consistent with, and strengthened by, recent findings from over 40 animal studies published since 1992. As with the studies on humans, the studies on animals have reported an impairment in learning and memory processes among the fluoride-treated groups.
  7. The animal studies have also documented considerable evidence of direct toxic effects of fluoride on brain tissue, even at levels as low as 1 ppm fluoride in water (Varner 1998). These effects include:
    • reduction in nicotinic acetylcholine receptors;
    • reduction in lipid content;
    • impaired anti-oxidant defense systems;
    • damage to the hippocampus;
    • damage to the purkinje cells;
    • increased uptake of aluminum;
    • formation of beta-amyloid plaques (classic brain abnormality in Alzheimer's disease)
    • exacerbation of lesions induced by iodine deficiency; and
    • accumulation of fluoride in the pineal gland.
    "It is apparent that fluorides have the ability to interfere with the functions of the brain." (SOURCE: National Research Council. (2006). Fluoride in Drinking Water: A Scientific Review of EPA's Standards. National Academies Press, Washington D.C. p 187.)


High doses of fluoride have repeatedly been found to interfere with the reproductive system of animals. Commonly observed effects in fluoride-exposed animals include: oxidative stress, damaged sperm, reduced sperm count, and reduced fertility. According to the authors of a recent study in the journal Reproductive Toxicology: "We conclude that fluoride treatment is associated with testicular disorders, which may be due to induction of oxidative stress in reproductive organs along with possible adverse effects of fluoride on pituitary testicular axis. The detailed mechanism of fluoride treatment on the male reproductive system has not been elucidated and will be the subject of future experiments " (Ghosh et al 2002).

Research on possible reproductive effects in humans is limited. Some recent research, however, indicates that fluoride exposure (at lower doses than given to animals) can cause toxic effects to human Sertoli cells and gonadotrophs, reduction in circulating testosterone, and reductions in total fertility rate. The dose at which fluoride can begin to cause these effects is not yet known.


  1. The vast majority of animal studies investigating fluoride's effect on bone strength, have found fluoride to have either no effect or a negative effect on strength. Very few animal studies have found a beneficial effect.
  2. Studies on human populations consuming fluoride in drinking water, have found an association between dental fluorosis and increased bone fracture in children; and between long-term consumption of fluoridated water and increased hip fracture in the elderly.
  3. Carefully conducted human clinical trials - including two "double-blind trials" - have found that fluoride (at doses of 18-34 mg/day for just 1-4 years) increases the rate of bone fracture, particularly hip fracture, among osteoporosis patients.
  4. Animal studies and human clinical trials indicate that fluoride can reduce bone strength before skeletal fluorosis is present.